Hydrogel formulation based microneedle adhesive patch

The present invention relates to a microneedle patch comprising: a first hydrogel layer including mussel adhesive protein and hyaluronic acid; and a second hydrogel layer including silk fibroin, and to a manufacturing method thereof. The microneedle patch according to the present invention exhibits...

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Hauptverfasser: LIM GEUN BAE, CHA HYUNG JOON, LEE JUNG HO, JEON EUN YOUNG
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Sprache:eng ; kor
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creator LIM GEUN BAE
CHA HYUNG JOON
LEE JUNG HO
JEON EUN YOUNG
description The present invention relates to a microneedle patch comprising: a first hydrogel layer including mussel adhesive protein and hyaluronic acid; and a second hydrogel layer including silk fibroin, and to a manufacturing method thereof. The microneedle patch according to the present invention exhibits excellent tissue adhesion, biocompatibility, biodegradability and can be utilized for drug delivery into the sclerite to promote wound regeneration. 본 발명은 홍합 접착 단백질 및 히알루론산을 포함하는 제1 하이드로겔 층 및 실크 피브로인을 포함하는 제2 하이드로겔 층을 포함하는 마이크로니들 패치, 및 그 제조 방법에 관한 것으로서, 본 발명에 따른 마이크로니들 패치는 우수한 조직 접착력, 생체 적합성, 생분해성을 나타내며, 상처 재생 촉진을 위한 경피로의 약물 전달에 활용될 수 있다.
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STENTS</topic><topic>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</topic><topic>FILTERS IMPLANTABLE INTO BLOOD VESSELS</topic><topic>FIRST-AID KITS</topic><topic>FOMENTATION</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</topic><topic>ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES</topic><topic>PROSTHESES</topic><topic>TREATMENT OR PROTECTION OF EYES OR EARS</topic><toplevel>online_resources</toplevel><creatorcontrib>LIM GEUN BAE</creatorcontrib><creatorcontrib>CHA HYUNG JOON</creatorcontrib><creatorcontrib>LEE JUNG HO</creatorcontrib><creatorcontrib>JEON EUN YOUNG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LIM GEUN BAE</au><au>CHA HYUNG JOON</au><au>LEE JUNG HO</au><au>JEON EUN YOUNG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Hydrogel formulation based microneedle adhesive patch</title><date>2019-11-27</date><risdate>2019</risdate><abstract>The present invention relates to a microneedle patch comprising: a first hydrogel layer including mussel adhesive protein and hyaluronic acid; and a second hydrogel layer including silk fibroin, and to a manufacturing method thereof. 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subjects BANDAGES, DRESSINGS OR ABSORBENT PADS
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY
DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
FILTERS IMPLANTABLE INTO BLOOD VESSELS
FIRST-AID KITS
FOMENTATION
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES
PROSTHESES
TREATMENT OR PROTECTION OF EYES OR EARS
title Hydrogel formulation based microneedle adhesive patch
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