Hydrogel formulation based microneedle adhesive patch

The present invention relates to a microneedle patch comprising: a first hydrogel layer including mussel adhesive protein and hyaluronic acid; and a second hydrogel layer including silk fibroin, and to a manufacturing method thereof. The microneedle patch according to the present invention exhibits...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	LIM GEUN BAE, CHA HYUNG JOON, LEE JUNG HO, JEON EUN YOUNG
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	BANDAGES, DRESSINGS OR ABSORBENT PADS CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS DISINFECTION, STERILISATION, OR DEODORISATION OF AIR FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PROSTHESES TREATMENT OR PROTECTION OF EYES OR EARS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to a microneedle patch comprising: a first hydrogel layer including mussel adhesive protein and hyaluronic acid; and a second hydrogel layer including silk fibroin, and to a manufacturing method thereof. The microneedle patch according to the present invention exhibits excellent tissue adhesion, biocompatibility, biodegradability and can be utilized for drug delivery into the sclerite to promote wound regeneration. 본 발명은 홍합 접착 단백질 및 히알루론산을 포함하는 제1 하이드로겔 층 및 실크 피브로인을 포함하는 제2 하이드로겔 층을 포함하는 마이크로니들 패치, 및 그 제조 방법에 관한 것으로서, 본 발명에 따른 마이크로니들 패치는 우수한 조직 접착력, 생체 적합성, 생분해성을 나타내며, 상처 재생 촉진을 위한 경피로의 약물 전달에 활용될 수 있다.