RIG-1 Implementation of Surface Repeating Structure Dextran Nanogels binding to Pattern Recognition Retinoic acid-Inducible Gene-I-like Receptors
The present invention relates to surface repeating structure implementation dextran nanogels that binds to a pattern recognition RIG-1 like receptor. Dextran nanoparticles of the present invention has little toxicity and side effects, has long-term stability, and also mediates innate immune activati...
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| creator | LEE BEOM JOO LEE JOONG BOK KANG YOUNG SUN CHOI SO YOUNG CHOI JONG CHUL PAIK HYUN JONG KIM DONG WOO CHOI IN SOO YANG SEUNG WOO LEE CHAE YEON CHOI HWI YEON LEEJA JOSE KIM MIM KYUNG |
| description | The present invention relates to surface repeating structure implementation dextran nanogels that binds to a pattern recognition RIG-1 like receptor. Dextran nanoparticles of the present invention has little toxicity and side effects, has long-term stability, and also mediates innate immune activation through a RIG-1 like receptor (RLR), a pattern recognition receptor, thereby having an effect of inhibiting proliferation of various viruses. Therefore, dextran nanoparticles can be usefully used for a pharmaceutical composition, a food composition or a feed composition for innate immunity promotion or anti-virus.
본 발명은 패턴인식 RIG-1 유사 수용체와 결합하는 표면 반복구조 구현 덱스트란 나노젤에 관한 것으로, 본 발명의 덱스트란 나노입자는 독성 및 부작용이 거의 없고 장기간 안정성을 지니며, 또한, 패턴인식수용체인 RIG-1 유사 수용체 (RIG-1 like receptor, RLR)를 통해 선천성 면역 활성화를 매개하고, 이에따라 다양한 바이러스의 증식을 억제할 수 있는 효과가 있어, 선천면역 증진 또는 항바이러스용 약학적 조성물, 식품 조성물 또는 사료 조성물 등에 유용하게 이용될 수 있다. |
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본 발명은 패턴인식 RIG-1 유사 수용체와 결합하는 표면 반복구조 구현 덱스트란 나노젤에 관한 것으로, 본 발명의 덱스트란 나노입자는 독성 및 부작용이 거의 없고 장기간 안정성을 지니며, 또한, 패턴인식수용체인 RIG-1 유사 수용체 (RIG-1 like receptor, RLR)를 통해 선천성 면역 활성화를 매개하고, 이에따라 다양한 바이러스의 증식을 억제할 수 있는 효과가 있어, 선천면역 증진 또는 항바이러스용 약학적 조성물, 식품 조성물 또는 사료 조성물 등에 유용하게 이용될 수 있다.</description><language>eng ; kor</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190729&DB=EPODOC&CC=KR&NR=20190088913A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190729&DB=EPODOC&CC=KR&NR=20190088913A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LEE BEOM JOO</creatorcontrib><creatorcontrib>LEE JOONG BOK</creatorcontrib><creatorcontrib>KANG YOUNG SUN</creatorcontrib><creatorcontrib>CHOI SO YOUNG</creatorcontrib><creatorcontrib>CHOI JONG CHUL</creatorcontrib><creatorcontrib>PAIK HYUN JONG</creatorcontrib><creatorcontrib>KIM DONG WOO</creatorcontrib><creatorcontrib>CHOI IN SOO</creatorcontrib><creatorcontrib>YANG SEUNG WOO</creatorcontrib><creatorcontrib>LEE CHAE YEON</creatorcontrib><creatorcontrib>CHOI HWI YEON</creatorcontrib><creatorcontrib>LEEJA JOSE</creatorcontrib><creatorcontrib>KIM MIM KYUNG</creatorcontrib><title>RIG-1 Implementation of Surface Repeating Structure Dextran Nanogels binding to Pattern Recognition Retinoic acid-Inducible Gene-I-like Receptors</title><description>The present invention relates to surface repeating structure implementation dextran nanogels that binds to a pattern recognition RIG-1 like receptor. Dextran nanoparticles of the present invention has little toxicity and side effects, has long-term stability, and also mediates innate immune activation through a RIG-1 like receptor (RLR), a pattern recognition receptor, thereby having an effect of inhibiting proliferation of various viruses. Therefore, dextran nanoparticles can be usefully used for a pharmaceutical composition, a food composition or a feed composition for innate immunity promotion or anti-virus.
본 발명은 패턴인식 RIG-1 유사 수용체와 결합하는 표면 반복구조 구현 덱스트란 나노젤에 관한 것으로, 본 발명의 덱스트란 나노입자는 독성 및 부작용이 거의 없고 장기간 안정성을 지니며, 또한, 패턴인식수용체인 RIG-1 유사 수용체 (RIG-1 like receptor, RLR)를 통해 선천성 면역 활성화를 매개하고, 이에따라 다양한 바이러스의 증식을 억제할 수 있는 효과가 있어, 선천면역 증진 또는 항바이러스용 약학적 조성물, 식품 조성물 또는 사료 조성물 등에 유용하게 이용될 수 있다.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjk0KwjAUhLtxIeodHrgOtLrRpfhbBJHqXtJ0WoLxJaSv4DW8sVU8gKuBYeabGSavIt-rjPJHcHiARYv1TL6mSxdrbUAFAnqTG7pI7Ix0EbTBU6JmOmn2DVxLpeXqExFPZy2CyH3P-IbtF1egB3hrSBtbqZyrztjSgfZgqFw5e__sGATxsR0ng1q7FpOfjpLpbntdHxSCv6EN_SmG3I7FLM2WabpYLLP5av5f6g1hJE-M</recordid><startdate>20190729</startdate><enddate>20190729</enddate><creator>LEE BEOM JOO</creator><creator>LEE JOONG BOK</creator><creator>KANG YOUNG SUN</creator><creator>CHOI SO YOUNG</creator><creator>CHOI JONG CHUL</creator><creator>PAIK HYUN JONG</creator><creator>KIM DONG WOO</creator><creator>CHOI IN SOO</creator><creator>YANG SEUNG WOO</creator><creator>LEE CHAE YEON</creator><creator>CHOI HWI YEON</creator><creator>LEEJA JOSE</creator><creator>KIM MIM KYUNG</creator><scope>EVB</scope></search><sort><creationdate>20190729</creationdate><title>RIG-1 Implementation of Surface Repeating Structure Dextran Nanogels binding to Pattern Recognition Retinoic acid-Inducible Gene-I-like Receptors</title><author>LEE BEOM JOO ; LEE JOONG BOK ; KANG YOUNG SUN ; CHOI SO YOUNG ; CHOI JONG CHUL ; PAIK HYUN JONG ; KIM DONG WOO ; CHOI IN SOO ; YANG SEUNG WOO ; LEE CHAE YEON ; CHOI HWI YEON ; LEEJA JOSE ; KIM MIM KYUNG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20190088913A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; kor</language><creationdate>2019</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>LEE BEOM JOO</creatorcontrib><creatorcontrib>LEE JOONG BOK</creatorcontrib><creatorcontrib>KANG YOUNG SUN</creatorcontrib><creatorcontrib>CHOI SO YOUNG</creatorcontrib><creatorcontrib>CHOI JONG CHUL</creatorcontrib><creatorcontrib>PAIK HYUN JONG</creatorcontrib><creatorcontrib>KIM DONG WOO</creatorcontrib><creatorcontrib>CHOI IN SOO</creatorcontrib><creatorcontrib>YANG SEUNG WOO</creatorcontrib><creatorcontrib>LEE CHAE YEON</creatorcontrib><creatorcontrib>CHOI HWI YEON</creatorcontrib><creatorcontrib>LEEJA JOSE</creatorcontrib><creatorcontrib>KIM MIM KYUNG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LEE BEOM JOO</au><au>LEE JOONG BOK</au><au>KANG YOUNG SUN</au><au>CHOI SO YOUNG</au><au>CHOI JONG CHUL</au><au>PAIK HYUN JONG</au><au>KIM DONG WOO</au><au>CHOI IN SOO</au><au>YANG SEUNG WOO</au><au>LEE CHAE YEON</au><au>CHOI HWI YEON</au><au>LEEJA JOSE</au><au>KIM MIM KYUNG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>RIG-1 Implementation of Surface Repeating Structure Dextran Nanogels binding to Pattern Recognition Retinoic acid-Inducible Gene-I-like Receptors</title><date>2019-07-29</date><risdate>2019</risdate><abstract>The present invention relates to surface repeating structure implementation dextran nanogels that binds to a pattern recognition RIG-1 like receptor. Dextran nanoparticles of the present invention has little toxicity and side effects, has long-term stability, and also mediates innate immune activation through a RIG-1 like receptor (RLR), a pattern recognition receptor, thereby having an effect of inhibiting proliferation of various viruses. Therefore, dextran nanoparticles can be usefully used for a pharmaceutical composition, a food composition or a feed composition for innate immunity promotion or anti-virus.
본 발명은 패턴인식 RIG-1 유사 수용체와 결합하는 표면 반복구조 구현 덱스트란 나노젤에 관한 것으로, 본 발명의 덱스트란 나노입자는 독성 및 부작용이 거의 없고 장기간 안정성을 지니며, 또한, 패턴인식수용체인 RIG-1 유사 수용체 (RIG-1 like receptor, RLR)를 통해 선천성 면역 활성화를 매개하고, 이에따라 다양한 바이러스의 증식을 억제할 수 있는 효과가 있어, 선천면역 증진 또는 항바이러스용 약학적 조성물, 식품 조성물 또는 사료 조성물 등에 유용하게 이용될 수 있다.</abstract><oa>free_for_read</oa></addata></record> |
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| title | RIG-1 Implementation of Surface Repeating Structure Dextran Nanogels binding to Pattern Recognition Retinoic acid-Inducible Gene-I-like Receptors |
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