METHOD FOR PRODUCING BACTERIAL GHOST AND VECTOR FOR PRODUCING BACTERIAL GHOST

The present invention relates to a ghost vaccine strain transformed by a vector comprising a cassette comprising an Rz gene, endolysin gene and holin gene of bacteriophage, a vector for the production thereof, a composition comprising the same, and a method for producing bacterial ghost. The new gho...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WON GA YEON, LEE JOHN HWA
Format: Patent
Sprache:eng ; kor
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Beschreibung
Zusammenfassung:The present invention relates to a ghost vaccine strain transformed by a vector comprising a cassette comprising an Rz gene, endolysin gene and holin gene of bacteriophage, a vector for the production thereof, a composition comprising the same, and a method for producing bacterial ghost. The new ghost vaccine strain of the present invention can induce improved immunogenicity over existing ghost vaccines. 본원은, 박테리오파지의 홀린(holin) 유전자, 엔도라이신(endolysin) 유전자 및 Rz 유전자를 포함하는 카제트(cassette)를 포함하는 벡터에 의해 형질전환된 고스트 백신 균주, 이의 제조를 위한 벡터, 이를 포함하는 조성물 및 세균 고스트 제조 방법에 관한 것이다.