A ANTIBODIES AGAINST BOTULINUM TOXIN TYPE A

The present invention relates to an antibody for treating botulism. The present invention, a humanized antibody that neutralizes botulinum toxin type A, provides the antibody consisting of a heavy chain region and a light chain region, wherein the heavy chain region has an amino acid sequence of SEQ...

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Bibliographische Detailangaben
Hauptverfasser:	KIM, CHANG HWAN, HUR, GYEUNG HAENG, SONG, DONG HYUN, YU, CHI HO, JUNG, HYUN HO, JUN, SEUNG CHUL, SHIN, YOUNG KEE, CHOI, JUN YOUNG, JEONG, SEONG TAE
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to an antibody for treating botulism. The present invention, a humanized antibody that neutralizes botulinum toxin type A, provides the antibody consisting of a heavy chain region and a light chain region, wherein the heavy chain region has an amino acid sequence of SEQ ID NO: 7, and the light chain region has the amino acid sequence of SEQ ID NO: 8. 본 발명은 보툴리눔 중독증의 치료용 항체에 관한 것이다. 본 발명은, 보툴리눔 독소 A형을 중화하는 인간화 항체로서, 상기 항체는 중쇄 영역 및 경쇄 영역을 포함하며, 상기 중쇄 영역은 서열번호 7의 아미노산 서열을 가지고, 상기 경쇄 영역은 서열번호 8의 아미노산 서열을 가지는 것을 특징으로 하는 항체를 제공한다.