e6- NOVEL CHLORIN E6-CURCUMIN DERIVATIVES PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR TREATMENT OF CANCER
The present invention relates to a novel chlorin e6-curcumin derivative, a manufacturing method thereof and a pharmaceutical composition containing the same for a cancer treatment. Especially, a novel composition is manufactured by using different linkers such as hydrophobic and hydrophilic linkers...
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| creator | SON, KWANG HEE KIM, YONG WAN LEE, HWAN SUK SHIVAKUMAR S JALDE |
| description | The present invention relates to a novel chlorin e6-curcumin derivative, a manufacturing method thereof and a pharmaceutical composition containing the same for a cancer treatment. Especially, a novel composition is manufactured by using different linkers such as hydrophobic and hydrophilic linkers to combine a chlorin e6 with a curcumin. The manufactured composition has superior photophysical properties, stability and an anticancer activity effect.
본 발명은 신규한 클로린 e6-커큐민 유도체, 그 제조방법 및 그것을 함유하는 암 치료용 약학 조성물에 관한 것으로서, 특히, 신규한 화합물은 클로린 e6를 커큐민에 결합시키기 위해 소수성 및 친수성 링커와 같이 서로 다른 링커를 사용함으로써 제조되며, 제조된 화합물은 우수한 광물리적 성질, 안정성 및 항암활성이 나타나는 효과가 있다. |
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본 발명은 신규한 클로린 e6-커큐민 유도체, 그 제조방법 및 그것을 함유하는 암 치료용 약학 조성물에 관한 것으로서, 특히, 신규한 화합물은 클로린 e6를 커큐민에 결합시키기 위해 소수성 및 친수성 링커와 같이 서로 다른 링커를 사용함으로써 제조되며, 제조된 화합물은 우수한 광물리적 성질, 안정성 및 항암활성이 나타나는 효과가 있다.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjMGKAkEMROfiYXH9h4DnAV3BxWPIZOxm7WTIZOYqIu1JVND_2F-2d_EDrEtVwav6qH7zugbRkXdAYacWBXhd02A0pJIbtjiix5F76Iw7tFJUILEHbcADG2sLKA10AS0h8eCRsLxp6rSP_zSpOEaJsv1bQI-JoVUDN0ZPLA7lg1CI7bOanA7ne569fFrNW3YKdb5d9_l-OxzzJT_2P_a1WG4WRZvvJa7eo54YlUEl</recordid><startdate>20190104</startdate><enddate>20190104</enddate><creator>SON, KWANG HEE</creator><creator>KIM, YONG WAN</creator><creator>LEE, HWAN SUK</creator><creator>SHIVAKUMAR S JALDE</creator><scope>EVB</scope></search><sort><creationdate>20190104</creationdate><title>e6- NOVEL CHLORIN E6-CURCUMIN DERIVATIVES PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR TREATMENT OF CANCER</title><author>SON, KWANG HEE ; KIM, YONG WAN ; LEE, HWAN SUK ; SHIVAKUMAR S JALDE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20190000971A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; kor</language><creationdate>2019</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>SON, KWANG HEE</creatorcontrib><creatorcontrib>KIM, YONG WAN</creatorcontrib><creatorcontrib>LEE, HWAN SUK</creatorcontrib><creatorcontrib>SHIVAKUMAR S JALDE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SON, KWANG HEE</au><au>KIM, YONG WAN</au><au>LEE, HWAN SUK</au><au>SHIVAKUMAR S JALDE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>e6- NOVEL CHLORIN E6-CURCUMIN DERIVATIVES PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR TREATMENT OF CANCER</title><date>2019-01-04</date><risdate>2019</risdate><abstract>The present invention relates to a novel chlorin e6-curcumin derivative, a manufacturing method thereof and a pharmaceutical composition containing the same for a cancer treatment. Especially, a novel composition is manufactured by using different linkers such as hydrophobic and hydrophilic linkers to combine a chlorin e6 with a curcumin. The manufactured composition has superior photophysical properties, stability and an anticancer activity effect.
본 발명은 신규한 클로린 e6-커큐민 유도체, 그 제조방법 및 그것을 함유하는 암 치료용 약학 조성물에 관한 것으로서, 특히, 신규한 화합물은 클로린 e6를 커큐민에 결합시키기 위해 소수성 및 친수성 링커와 같이 서로 다른 링커를 사용함으로써 제조되며, 제조된 화합물은 우수한 광물리적 성질, 안정성 및 항암활성이 나타나는 효과가 있다.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | e6- NOVEL CHLORIN E6-CURCUMIN DERIVATIVES PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR TREATMENT OF CANCER |
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