Method for detecting diagnosing marker of cancer-specific in whole genome sequence

The present invention relates to detection of a cancer-specific diagnostic marker in genome and, more specifically, to a method for detecting a cancer-specific biomarker with high accuracy by grasping a relationship between cancer and genetic variation to detect a cancer-specific genetic change. The method comprises the steps of: inputting whole genome sequencing information of a cancer sample and a normal sample; comparing and/or contrasting the whole genome sequencing information with reference genome sequence information to obtain analyzed information; deriving a disease classification chart from the analyzed information and sample information; constructing a library for cancer-specific base sequence information in the whole genome sequencing information of the cancer sample and the normal sample using the disease classification chart; and deriving classification accuracy according to a change in the disease classification chart and the number of base variation from the constructed library. 본 발명은 유전체 내의 암 특이적 진단 마커 검출 방법에 관한 것으로, 더욱 상세하게는 암과 유전체 변이의 관계를 파악하여 암 특이적인 유전체 변화를 검출함으로써, 정확도 높은 암 특이적 바이오 마커를 검출할 수 있는 방법이다.