Composition comprising long-acting Erythropoietin
The present invention relates to a composition containing long-lasting erythropoietin and a manufacturing method thereof and, more specifically, to an EPO-Fc fusion protein composition and a manufacturing method thereof. The EPO-Fc fusion protein composition has an excellent long-lasting feature and...
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| creator | CHUNG YO KYUNG SUNG YOUNG CHUL YANG SE HWAN YANG SANG IN WOO JUNG WON KIM MIN WOO HAN SEUNG RYEL |
| description | The present invention relates to a composition containing long-lasting erythropoietin and a manufacturing method thereof and, more specifically, to an EPO-Fc fusion protein composition and a manufacturing method thereof. The EPO-Fc fusion protein composition has an excellent long-lasting feature and high purity by including sialic acid of EPO-Fc and host cell protein impurities wherein a content of the sialic acid of EPO-Fc is 17 mol/mol or more and the host cell protein impurities are 100 ng/mg or less.
본 발명은 지속형 에리트로포이에틴 함유 조성물 및 그 제조방법에 관한 것으로서, 보다 상세하게는 EPO-Fc의 시알릭산 함량이 17 mol/mol 이상이고, 숙주세포 유래 단백질(HCP) 불순물이 100 ng/mg 이하로 포함됨으로써 생체 내 지속성이 우수하고 순도가 높은 EPO-Fc 융합 단백질 조성물 및 그 제조방법에 관한 것이다. |
| format | Patent |
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본 발명은 지속형 에리트로포이에틴 함유 조성물 및 그 제조방법에 관한 것으로서, 보다 상세하게는 EPO-Fc의 시알릭산 함량이 17 mol/mol 이상이고, 숙주세포 유래 단백질(HCP) 불순물이 100 ng/mg 이하로 포함됨으로써 생체 내 지속성이 우수하고 순도가 높은 EPO-Fc 융합 단백질 조성물 및 그 제조방법에 관한 것이다.</description><language>eng ; kor</language><subject>CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180313&DB=EPODOC&CC=KR&NR=20180026688A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180313&DB=EPODOC&CC=KR&NR=20180026688A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHUNG YO KYUNG</creatorcontrib><creatorcontrib>SUNG YOUNG CHUL</creatorcontrib><creatorcontrib>YANG SE HWAN</creatorcontrib><creatorcontrib>YANG SANG IN</creatorcontrib><creatorcontrib>WOO JUNG WON</creatorcontrib><creatorcontrib>KIM MIN WOO</creatorcontrib><creatorcontrib>HAN SEUNG RYEL</creatorcontrib><title>Composition comprising long-acting Erythropoietin</title><description>The present invention relates to a composition containing long-lasting erythropoietin and a manufacturing method thereof and, more specifically, to an EPO-Fc fusion protein composition and a manufacturing method thereof. The EPO-Fc fusion protein composition has an excellent long-lasting feature and high purity by including sialic acid of EPO-Fc and host cell protein impurities wherein a content of the sialic acid of EPO-Fc is 17 mol/mol or more and the host cell protein impurities are 100 ng/mg or less.
본 발명은 지속형 에리트로포이에틴 함유 조성물 및 그 제조방법에 관한 것으로서, 보다 상세하게는 EPO-Fc의 시알릭산 함량이 17 mol/mol 이상이고, 숙주세포 유래 단백질(HCP) 불순물이 100 ng/mg 이하로 포함됨으로써 생체 내 지속성이 우수하고 순도가 높은 EPO-Fc 융합 단백질 조성물 및 그 제조방법에 관한 것이다.</description><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDB0zs8tyC_OLMnMz1NIBrKLMosz89IVcvLz0nUTk0tAbNeiypKMovyC_MxUIJ-HgTUtMac4lRdKczMou7mGOHvophbkx6cWFyQmp-allsR7BxkZGFoYGBiZmVlYOBoTpwoAou8tbQ</recordid><startdate>20180313</startdate><enddate>20180313</enddate><creator>CHUNG YO KYUNG</creator><creator>SUNG YOUNG CHUL</creator><creator>YANG SE HWAN</creator><creator>YANG SANG IN</creator><creator>WOO JUNG WON</creator><creator>KIM MIN WOO</creator><creator>HAN SEUNG RYEL</creator><scope>EVB</scope></search><sort><creationdate>20180313</creationdate><title>Composition comprising long-acting Erythropoietin</title><author>CHUNG YO KYUNG ; SUNG YOUNG CHUL ; YANG SE HWAN ; YANG SANG IN ; WOO JUNG WON ; KIM MIN WOO ; HAN SEUNG RYEL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20180026688A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; kor</language><creationdate>2018</creationdate><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><toplevel>online_resources</toplevel><creatorcontrib>CHUNG YO KYUNG</creatorcontrib><creatorcontrib>SUNG YOUNG CHUL</creatorcontrib><creatorcontrib>YANG SE HWAN</creatorcontrib><creatorcontrib>YANG SANG IN</creatorcontrib><creatorcontrib>WOO JUNG WON</creatorcontrib><creatorcontrib>KIM MIN WOO</creatorcontrib><creatorcontrib>HAN SEUNG RYEL</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CHUNG YO KYUNG</au><au>SUNG YOUNG CHUL</au><au>YANG SE HWAN</au><au>YANG SANG IN</au><au>WOO JUNG WON</au><au>KIM MIN WOO</au><au>HAN SEUNG RYEL</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Composition comprising long-acting Erythropoietin</title><date>2018-03-13</date><risdate>2018</risdate><abstract>The present invention relates to a composition containing long-lasting erythropoietin and a manufacturing method thereof and, more specifically, to an EPO-Fc fusion protein composition and a manufacturing method thereof. The EPO-Fc fusion protein composition has an excellent long-lasting feature and high purity by including sialic acid of EPO-Fc and host cell protein impurities wherein a content of the sialic acid of EPO-Fc is 17 mol/mol or more and the host cell protein impurities are 100 ng/mg or less.
본 발명은 지속형 에리트로포이에틴 함유 조성물 및 그 제조방법에 관한 것으로서, 보다 상세하게는 EPO-Fc의 시알릭산 함량이 17 mol/mol 이상이고, 숙주세포 유래 단백질(HCP) 불순물이 100 ng/mg 이하로 포함됨으로써 생체 내 지속성이 우수하고 순도가 높은 EPO-Fc 융합 단백질 조성물 및 그 제조방법에 관한 것이다.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES |
| title | Composition comprising long-acting Erythropoietin |
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