COMPOSITION FOR TRANSDERMAL DELIVERY COMPRISING NANOEMULSION AND MODIFIED LAYERED DOUBLE HYDROXIDE

The present invention relates to a multilamellar vesicle containing retinol, and more specifically, to a multilamellar vesicle containing retinol which contains: 1) retinol-containing nanoemulsion containing retinol, hydrogenated lecithin, phytosteryl macadamiate, heavy chain triglyceride, and water...

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Bibliographische Detailangaben
Hauptverfasser: LEE, JONG HYEON, PARK, YOUNG AH, CHO, SE HEE, WOO, YOUNG RONG, JI, HONG GEUN
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:The present invention relates to a multilamellar vesicle containing retinol, and more specifically, to a multilamellar vesicle containing retinol which contains: 1) retinol-containing nanoemulsion containing retinol, hydrogenated lecithin, phytosteryl macadamiate, heavy chain triglyceride, and water; 2) layered double hydroxide; 3) phosphatidylcholine; 4) hexanediol; 5) glycerin; 6) heavy chain triglyceride; and 7) water. The present invention also relates to a manufacturing method of the multilamellar vesicle. 본 발명은 레티놀 함유 멀티라멜라 소포에 관한 것으로, 보다 상세하게는 1) 레티놀, 하이드로제네이티드 레시틴, 피토스테릴 마카다미에이트, 중쇄 트리글리세라이드 및 물을 포함하는 레티놀 함유 나노에멀젼; 2) 층상 이중 수산화물; 3) 포스파티딜콜린; 4) 헥산디올; 5) 글리세린; 6) 중쇄 트리글리세라이드; 및 7) 물을 포함하는 레티놀 함유 멀티라멜라 소포 및 이의 제조 방법에 관한 것이다.