A ANTIBACTERIAL LIPOSOME COMPOSITION CONTAINING CONJUGATE OF PHEOPHORBIDE A AND LIPID DERIVATIVE OF POLYETHYLENE GLYCOL

The present invention relates to an antibacterial liposome composition containing a conjugate of pheophorbide A and a lipid derivative of polyethylene glycol, and more specifically, to an antibacterial liposome composition, which contains 0.0001 to 5 wt% of a conjugate of 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino (polyethylene glycol)-2000] and pheophorbide A, 1 to 10 wt% of polyglyceryl-3-methyl glucoside distearate, 1 to 10 wt% of polysorbate 80, 5 to 40 wt% of cetyl palmitate, 1 to 10 wt% of vegetable oil, 2 to 15 wt% of N-methyl-2-pyrrolidone and a residual amount of water. The present invention provides a composition which can effectively use pheophorbide A, which is a photosensitizer, into skin to exhibit excellent antibacterial activity and thus can be effectively used for the treatment of acne and the like. 본 발명은 페오포르비드 A 및 폴리에틸렌글리콜의 지질 유도체의 결합체를 함유하는 항균 리포좀 조성물에 관한 것으로, 보다 상세하게는 1,2-디스테아로일-sn-글리세로-3-포스포에탄올아민-N-[아미노(폴리에틸렌글리콜)-2000]과 페오포르비드 A의 결합체 0.0001 내지 5 중량%, 폴리글리세릴-3-메틸글루코오스디스테아레이트 1 내지 10 중량%, 폴리소르베이트 80 1 내지 10 중량%, 세틸 팔미테이트 5 내지 40 중량%, 식물성 오일 1 내지 10 중량%, N-메틸-2-피롤리돈 2 내지 15 중량% 및 잔량의 물을 포함하는 항균 리포좀 조성물에 관한 것이다.