9 A cosmetic composition for hair care comprising high stable Fibroblast Growth Factor-9 mutant

The present invention relates to a hair care cosmetic composition comprising, as an active ingredient, a highly stable fibroblast growth factor-9 mutant promoting the regeneration and growth of hair follicle cells, and additionally containing a basic fibroblast growth factor mutant having increased...

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Bibliographische Detailangaben
Hauptverfasser: PARK, YEAN HEE, OH, JONG KWANG, SUN, SEUNG TAEK, SHIN, HANG CHEOL
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:The present invention relates to a hair care cosmetic composition comprising, as an active ingredient, a highly stable fibroblast growth factor-9 mutant promoting the regeneration and growth of hair follicle cells, and additionally containing a basic fibroblast growth factor mutant having increased stability and Noggin peptide. Specifically, the present invention relates to a cosmetic composition capable of achieving, through the regeneration and differentiation of hair follicle cells, the promotion of hair generation and growth, the inhibition of hair follicle cell apoptosis factors, the inhibition of androgenic hair loss, the improvement of blood circulation and the supply of nutritional factors. According to the present invention, hair follicle cell regeneration and growth is promoted and hair loss is prevented by using the cosmetic composition of the present invention, containing a growth factor complex comprising a growth factor, a highly stable fibroblast growth factor-9 mutant, a stabilized fibroblast growth factor mutant and Noggin peptide, thereby promoting hair growth and preventing hair loss. 본 발명은 모낭 세포의 재생 및 성장을 촉진하는 고안정성 섬유아세포 성장인자-9 변이체를 유효성분으로 포함하고, 추가적으로, 안정성이 증가된 염기성 섬유아세포 성장인자 변이체 및 노긴 펩타이드를 함유한 헤어케어 화장료 조성물에 관한 것으로, 더욱 상세하게, 본 발명은 모낭 세포의 재생과 분화를 통해 모발의 생성 및 성장 촉진, 모낭세포 세포사멸인자의 억제, 안드로겐성 탈모 억제 및 혈행개선과 영양인자 공급을 구현할 수 있는 화장료 조성물에 대한 것이다. 본 발명에 의하면, 본 발명의 성장인자, 고안정성 섬유아세포 성장인자-9 변이체, 안정화된 섬유아세포성장인자 변이체 및 노긴 펩타이드가 포함된 성장인자 콤플렉스를 함유한 화장료 조성물을 이용 모낭세포의 재생 및 성장을 촉진하여 발모를 촉진하고 탈모를 예방하는데 효과가 있다.