PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF OBESITY COMPRISING THE EXTRACTS OF SCHIZANDRA CHINENSIS AS ACTIVE INGREDIENT

The present invention relates to a pharmaceutical composition for preventing or treating obesity, containing a Schisandra chinensis fruit extract as an active ingredient. According to the present invention, the Schisandra chinensis fruit extract increases expression of PR domain containing 16 (PRDM16), peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1), and uncoupling protein-1 (UCP-1), which are genes involved in energy consumption in white fat cells. Thus, the composition of the present invention can be used as a brown fat-inducing substance or an anti-obesity substance and also as a pharmaceutical composition, a functional health food, a cosmetic composition, and a pharmaceutical composition for skin external application for inducing brown fat cells. 본 발명은 오미자() 추출물을 유효성분으로 함유하는 비만 예방 및 치료용 약학적 조성물에 관한 것으로, 오미자 추출물은 백색지방세포에서 에너지 소비에 관여하는 유전자인 UCP-1(Uncoupling protein-1), PGC-1α 및 PRDM16의 발현을 증가시키므로 본 발명의 조성물은 갈색지방 유도 물질 또는 항 비만 물질, 갈색지방세포 유도용 약학적 조성물, 건강기능식품, 화장료 조성물 및 피부 외용제 약학적 조성물로써 사용될 수 있다.