BIOSENSOR FOR DETECTING TARGET MATERIALS USING PROTEASE REACTION

A biosensor comprises: an electrode unit comprising a reference electrode and a working electrode separated from the reference electrode, on which a matrix of target protease bound to the target protease can be fixated; a lower substrate on which the electrode unit is formed; a micro channel which c...

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Bibliographische Detailangaben
Hauptverfasser:	AHN, GUK KI, HWANG, SEUNG YONG, AHN, YOO MIN, SEO, IN JAE
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	A biosensor comprises: an electrode unit comprising a reference electrode and a working electrode separated from the reference electrode, on which a matrix of target protease bound to the target protease can be fixated; a lower substrate on which the electrode unit is formed; a micro channel which comprises two or more electrode units and is formed on upper portions of the electrode units; and an upper substrate facing the lower substrate, wherein a mixture unit is formed on the micro channel. The biosensor measures a difference in impedance between the working electrode and the reference electrode before and after the target protease is bound. 본 발명은 기준전극 및 상기 기준전극과 소정간격 이격되어 형성되며, 표적단백질분해효소와 결합하는 표적단백질분해효소의 기질이 고정화될 수 있는 작업전극을 포함하는 전극부; 상기 전극부가 형성된 하부기판; 상기 전극부는 적어도 두 개를 포함하며, 상기 전극부의 상부에 형성된 미세채널; 상기 하부기판과 대향하며, 상기 미세채널 상에 혼합부가 형성된 상부기판; 을 포함하며, 상기 표적단백질분해효소의 결합 전 및 후의 상기 작업전극과 상기 기준전극의 임피던스 차이를 측정하는 바이오 센서에 관한 것이다.