STABILIZED PENICILLIN COMPLEX SUSPENSION PREPARATION

The present invention relates to a liquid penicillin complex suspension agent for injection containing benzylpenicillin. The liquid penicillin complex suspension agent includes antioxidants selected from a group of sodium bisulfite, sodium sulfite, motothioglycerol, formaldehyde sulfoxylate, ethylen...

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Bibliographische Detailangaben
Hauptverfasser: KIM, YOUNG IL, LIM, CHANG HYUN, KIM, HYUN SEUL, PARK, HYUK SOO, HWANG, SA RANG, JANG, YE SUN, KOO, DAE HWAN, LEE, KYU LIM, LEE, HYE WON, WOO, MI KYUNG, LEE, YE JI, SHIN, SUNG HWAN, KIM, JUNG WON, PARK, HYE YOUNG, LEE, HA NI, YOO, DA SO MI
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:The present invention relates to a liquid penicillin complex suspension agent for injection containing benzylpenicillin. The liquid penicillin complex suspension agent includes antioxidants selected from a group of sodium bisulfite, sodium sulfite, motothioglycerol, formaldehyde sulfoxylate, ethylene diamine tetra acetic acid (EDTA), sodium thiosulfate, sodium ascorbate, and combinations thereof. The antioxidants are added to enhance stability of the liquid penicillin complex suspension agent. Accordingly, the present invention can prevent the liquid penicillin complex suspension agent from dropping in potency due to the decomposition of active ingredients even when the liquid penicillin complex suspension agent is stored for an extended period of time.