1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE β-LACTAMASE INHIBITORS

1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE β-LACTAMASE INHIBITORS

-Lactamase inhibitor compounds (BLIs) are disclosed, including compounds that have activity against class A, class C or class D -lactamases. Methods of manufacturing the BLIs, and uses of the compounds in the preparation of pharmaceutical compositions and antibacterial applications are also disclose...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BUSCH ROBERT, ALEXANDER DYLAN C, YIN NING, GU YU GUI, METCALF CHESTER A. III, HE YONG, CROSS JASON B
Format: Patent
Sprache:eng ; kor
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:-Lactamase inhibitor compounds (BLIs) are disclosed, including compounds that have activity against class A, class C or class D -lactamases. Methods of manufacturing the BLIs, and uses of the compounds in the preparation of pharmaceutical compositions and antibacterial applications are also disclosed.