CRYSTALLINE PI3 KINASE INHIBITORS

There is provided inter alia 6-(2-((4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl) methyl)-3-(2-chlorobenzyl)-4-oxo-3,4-di hydroquinazolin-5-yl)-N, N-bis(2-methoxyethyl)hex-5-ynamide in the form of a solid crystalline hydrate and in solid crystalline anhydrous form. There are also pro...

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Bibliographische Detailangaben
Hauptverfasser: COPMANS ALEX HERMAN, LEYS CARINA, FILLIERS WALTER FERDINAND MARIA, NIESTE PATRICK HUBERT J, VANHOUTTE FILIP MARCEL C, BROECKX RUDY LAURENT MARIA
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:There is provided inter alia 6-(2-((4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl) methyl)-3-(2-chlorobenzyl)-4-oxo-3,4-di hydroquinazolin-5-yl)-N, N-bis(2-methoxyethyl)hex-5-ynamide in the form of a solid crystalline hydrate and in solid crystalline anhydrous form. There are also provided dry powder pharmaceutical compositions for inhalation containing such solid crystalline forms.