COMPOSITION FOR SCREENING SKIN IRRITANT AND METHOD FOR SCREENING SKIN IRRITANT USING THE SAME

The present invention relates to a composition for screening a skin irritant and a method for screening a skin irritant using the same. When PI3, CEBPA, SERP INB3, HOPX, SPRR1A, NOD2, LCE3D, CNFN, TMTC1, KRTDAP, ANKRD35, SBSN, BPIL2, RDH12, FLG, H19, FLG2, LOR, IVL, NLRX1, ALDH1A3, DSC2, RHCG, SCEL,...

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Bibliographische Detailangaben
Hauptverfasser:	LEE, AI YOUNG, NOH, MIN SOO, CHEONG, KYUNG AH, KIM, JI YOUNG
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a composition for screening a skin irritant and a method for screening a skin irritant using the same. When PI3, CEBPA, SERP INB3, HOPX, SPRR1A, NOD2, LCE3D, CNFN, TMTC1, KRTDAP, ANKRD35, SBSN, BPIL2, RDH12, FLG, H19, FLG2, LOR, IVL, NLRX1, ALDH1A3, DSC2, RHCG, SCEL, IL20, S100A8, S100A9, S100A12, BNIPL, SPRR3, TMEM79, FAM84A, GRHL1, SGPP2, AADACL2, TPRG1, PPP2R2C, SPINK5, ATP10B, GPR110, IL20RA, DEFB1, SLC28A3, AIF1L, CLIC3, NEBL, CARD18, PLBD1, GLTP, TGM1, ZNF750, DSC1, SERPINB13, EMR2, KLK10, COX7A1, SULT2B1, and KLK7 genes of the present invention are processed by general hydroquinone, retinoic acid, or SLS as a skin irritant, the expression amount is increased or decreased; thereby screening the harmful skin irritant using the genes. Thus, the present invention can be used as the method for screening a skin irritant instead of the prohibited animal experiment of cosmetic source materials.