HETEROCYCLIC BENZAMIDE DERIVATIVES AS CANNABINOID CB1 RECEPTOR ANTAGONISTS

The present invention relates to a novel heterocyclic benzamide compound or a pharmaceutically acceptable salt thereof which acts as an inverse-agonist or an antagonist of cannabinoid CB1 receptor. The compound, according to the present invention, can be valuably used for preventing or treating obes...

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Hauptverfasser: CHOI, EUN BOK, OH, JUNG TAEK, YANG, HEUI CHERL, KIM, KWANG ROK, LEE, HYEON KYU, JANG, TAEG SU
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creator CHOI, EUN BOK
OH, JUNG TAEK
YANG, HEUI CHERL
KIM, KWANG ROK
LEE, HYEON KYU
JANG, TAEG SU
description The present invention relates to a novel heterocyclic benzamide compound or a pharmaceutically acceptable salt thereof which acts as an inverse-agonist or an antagonist of cannabinoid CB1 receptor. The compound, according to the present invention, can be valuably used for preventing or treating obesity or obesity-related metabolic diseases. In addition, the present invention provides a method for manufacturing a heterocyclic benzamide compound, a pharmaceutical composition comprising the same, and a method for preventing or treating obesity and obesity-related metabolic diseases.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title HETEROCYCLIC BENZAMIDE DERIVATIVES AS CANNABINOID CB1 RECEPTOR ANTAGONISTS
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