PROCESS FOR PREPARING 1,2-BENZISOTHIAZOLIN-3-ONE

PROCESS FOR PREPARING 1,2-BENZISOTHIAZOLIN-3-ONE

Sodium sulfide hydrate is at least partially dehydrated by heating with N-methyl 2-pyrrolidone. 2-chlorobenzamide is added to the mixture which is heated further. The mixture is cooled and treated with aqueous hydrogen peroxide to give the sodium salt of 1,2-benzoisothiazoline-3-one in good yield. A...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BERG CARSTEN, SINGH SANGITA, HOULLEMARE DIDIER
Format: Patent
Sprache:eng ; kor
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Sodium sulfide hydrate is at least partially dehydrated by heating with N-methyl 2-pyrrolidone. 2-chlorobenzamide is added to the mixture which is heated further. The mixture is cooled and treated with aqueous hydrogen peroxide to give the sodium salt of 1,2-benzoisothiazoline-3-one in good yield. Acidification if desired gives rise to the free 1,2-benzoisothiazoline-3-one.