NOVEL URSOLIC ACID DERIVATIVES AND PREPARATION METHOD THEREOF

The present invention relates to a pro-drug form of ursolic acid which can have pharmacokinetic properties including excellent stability and oral absorption rate, specifically to: a novel ursolic acid derivative in a pro-drug form of ursolic acid capable of changing into ursolic acid in human body f...

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Hauptverfasser: YOON, YEO HONG, KWEON, DON SUN
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KWEON, DON SUN
description The present invention relates to a pro-drug form of ursolic acid which can have pharmacokinetic properties including excellent stability and oral absorption rate, specifically to: a novel ursolic acid derivative in a pro-drug form of ursolic acid capable of changing into ursolic acid in human body for offering an excellent pharmaceutical activity; and a preparation method thereof. The ursolic acid derivative can have an ester form in which a pro-drug of a predetermined pharmaceutical compound is combined to carboxyl acid in C28 of ursolic acid.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
title NOVEL URSOLIC ACID DERIVATIVES AND PREPARATION METHOD THEREOF
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