PROCESS FOR THE PREPARATION OF N-(2-HYDROXYETHYL)NICOTINAMIDE AND NICORANDIL

PROCESS FOR THE PREPARATION OF N-(2-HYDROXYETHYL)NICOTINAMIDE AND NICORANDIL

The present invention provides a new preparing method of N-(2-hydroxyethyl) nicotinamide and nicorandil capable of providing an increased yield rate and overcoming a weakness of taking a long time to synthesize N-(2-hydroxyethyl) nicotinamide by preparing the N-(2-hydroxyethyl) nicotinamide without...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HWANG, SUNG KWAN, YANG, WOO RAM, PARK, CHANG HA
Format: Patent
Sprache:eng ; kor
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention provides a new preparing method of N-(2-hydroxyethyl) nicotinamide and nicorandil capable of providing an increased yield rate and overcoming a weakness of taking a long time to synthesize N-(2-hydroxyethyl) nicotinamide by preparing the N-(2-hydroxyethyl) nicotinamide without a solvent like the reaction formula 1. [Reference numerals] (AA) N-(2-hydroxyethyl) nicotinamide XRD