TRANSDERMAL COMPOSITION COMPRISING ROTIGOTINE

The present invention relates to a method for preventing the crystallization of rotigotine. Further, the present invention relates to a method for preventing the precipitation of rotigotine crystals, wherein the method comprises a step of mixing rotigotine with at least one selected from the group c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	YOUN, WON NO, KIM, HUN TAEK, LM, JONG SEOB, PARK, YEO JIN, OH, JOON GYO, HWANG, YONG YOUN, KIM, HYE MIN
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention relates to a method for preventing the crystallization of rotigotine. Further, the present invention relates to a method for preventing the precipitation of rotigotine crystals, wherein the method comprises a step of mixing rotigotine with at least one selected from the group consisting of fatty alcohols, fatty acids, fatty acid esters, fatty acid amides, and derivatives thereof. Further, the present invention relates to a transdermal preparation comprising rotigotine and a crystallization inhibitor. The methods and systems of the present invention prevent the precipitation of rotigotine to improve the long-term storage stability, and thus can be effectively applied in the preparation of rotigotine-containing patches. [Reference numerals] (140) Controller; (150) Alarm generator; (AA) Low-concentration odor; (BB) High-concentration odor