RNA APTAMER THAT SELECTIVELY BINDS TO EXTRACELLULAR DOMAIN OF PAP

The present invention relates to a RNA aptamer which is selectively bound to extracellular domain of PAP having high correlation with morphological characteristics of prostate cancer, to a composition for diagnosing cancers which includes the RNA aptamer, to a kit for diagnosing cancers which includ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	BYUN, JONG HOE, KONG, HOON YOUNG
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a RNA aptamer which is selectively bound to extracellular domain of PAP having high correlation with morphological characteristics of prostate cancer, to a composition for diagnosing cancers which includes the RNA aptamer, to a kit for diagnosing cancers which includes the composition, a pharmaceutical composition for treating cancers which includes the RNA aptamer, and to a method for screening DNA pieces which are interacted with the extracellular domain of PAP using the RNA aptamer. The RNA aptamer of the present invention can be strongly bound to the extracellular domain of PAP which is specific to prostate cancer so that the RNA aptamer can be widely utilized for diagnosing or treating the prostate cancer.