COMPOSITION FOR DIAGNOSING CIRCULATING TUMOR CELLS AND METHOD FOR DETECTING CIRCULATING TUMOR CELLS USING THE SAME

PURPOSE: A composition for diagnosing circulating tumor cells (CTC) is provided to quickly and efficiently capture high purity circulating tumor cells. CONSTITUTION: A composition for diagnosing CTC contains: nanoparticles containing a primary antibody which specifically binds to CTC; and magnetic b...

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Hauptverfasser: MIN, HYE GEUN, JO, SEONG MIN, KIM, HAK SUNG
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Sprache:eng ; kor
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creator MIN, HYE GEUN
JO, SEONG MIN
KIM, HAK SUNG
description PURPOSE: A composition for diagnosing circulating tumor cells (CTC) is provided to quickly and efficiently capture high purity circulating tumor cells. CONSTITUTION: A composition for diagnosing CTC contains: nanoparticles containing a primary antibody which specifically binds to CTC; and magnetic beads containing a secondary antibody which binds to the primary antibody. A method for detecting CTC comprises the steps of: making the nanoparticles react with a sample containing CTC; centrifuging the reactant solution and removing unreacted nanoparticles; adding the magnetic beads and a buffer solution; and isolating nanoparticles conjugated with the primary antibody attached to the magnetic beads conjugated with CTC and the secondary antibody using a magnet.
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subjects INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES
MEASURING
NANOTECHNOLOGY
PERFORMING OPERATIONS
PHYSICS
SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
TESTING
TRANSPORTING
title COMPOSITION FOR DIAGNOSING CIRCULATING TUMOR CELLS AND METHOD FOR DETECTING CIRCULATING TUMOR CELLS USING THE SAME
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