COMPOSITION FOR DIAGNOSING CIRCULATING TUMOR CELLS AND METHOD FOR DETECTING CIRCULATING TUMOR CELLS USING THE SAME

PURPOSE: A composition for diagnosing circulating tumor cells (CTC) is provided to quickly and efficiently capture high purity circulating tumor cells. CONSTITUTION: A composition for diagnosing CTC contains: nanoparticles containing a primary antibody which specifically binds to CTC; and magnetic b...

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Bibliographische Detailangaben
Hauptverfasser:	MIN, HYE GEUN, JO, SEONG MIN, KIM, HAK SUNG
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MANUFACTURE OR TREATMENT OF NANOSTRUCTURES MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES MEASURING NANOTECHNOLOGY PERFORMING OPERATIONS PHYSICS SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES TESTING TRANSPORTING
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Beschreibung
Zusammenfassung:	PURPOSE: A composition for diagnosing circulating tumor cells (CTC) is provided to quickly and efficiently capture high purity circulating tumor cells. CONSTITUTION: A composition for diagnosing CTC contains: nanoparticles containing a primary antibody which specifically binds to CTC; and magnetic beads containing a secondary antibody which binds to the primary antibody. A method for detecting CTC comprises the steps of: making the nanoparticles react with a sample containing CTC; centrifuging the reactant solution and removing unreacted nanoparticles; adding the magnetic beads and a buffer solution; and isolating nanoparticles conjugated with the primary antibody attached to the magnetic beads conjugated with CTC and the secondary antibody using a magnet.