ENANTIOMERICALLY PURE BINAPHTOL DERIVATIVES AND METHOD FOR PREPARING THE SAME

PURPOSE: A manufacturing method of a binaphthol derivative is provided to efficiently introduce various substituents into hydrogen locations of a 2'-hydroxy group of a 2,2'-binaphthol-3-carboxylic acid and to safely and economically manufacture the binaphthol derivative. CONSTITUTION: A ma...

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Hauptverfasser:	KIM, JOON SEO, CHANG, RAE KYU, KOH, YOUNG KOOK, GA, HYE RIM, LEE, YOUNG HEE, AHN, YUN SOO, MAENG, JU WAN, YOON, HEUNG SIK, JUNG, HEE JUNG, LEE, KWANG JAE, LEE, HYUN IL
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY METALLURGY ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:	PURPOSE: A manufacturing method of a binaphthol derivative is provided to efficiently introduce various substituents into hydrogen locations of a 2'-hydroxy group of a 2,2'-binaphthol-3-carboxylic acid and to safely and economically manufacture the binaphthol derivative. CONSTITUTION: A manufacturing method of a binaphthol derivative represented by chemical formula 1 includes a step of conduct the reaction of a compound represented by chemical formula 2 and a compound represented by chemical formula 3 in an organic solvent under the presence of a base. The base is an organic base which is triethylamine or tetramethylethylenediamine or an inorganic base selected from NaH, NaOH, KOH, and K2CO3. The organic solvent is selected from N,N-dimethylformamide, dimethylsulfoxide, N-methylpyrrolidine, and tetrahydrofuran.