ANTI-DIABETIC COMPOUNDS

ANTI-DIABETIC COMPOUNDS

The present invention provides a FGF21 molecule covalently attached to the combining site of an antibody via a linker, wherein the linker is covalently attached to the side chain of a linking residue within FGF21. Various uses of the compounds are provided, including methods to prevent or treat diab...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: VIOLAND BERNARD NORMAN, LEVIN NANCY JANE, DAS TAPAN KANTI, PARSONS ERIN KRISTEN, ISHINO TETSUYA, HODGE TAMARA SHAFER, PALANKI MOORTHY SITHARAMAIAH SURIYANARAYANA
Format: Patent
Sprache:eng ; kor
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention provides a FGF21 molecule covalently attached to the combining site of an antibody via a linker, wherein the linker is covalently attached to the side chain of a linking residue within FGF21. Various uses of the compounds are provided, including methods to prevent or treat diabetes or diabetes-related conditions.