DERIVATIVES OF 1-PHENOXY PROPAN-2-OL AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

PURPOSE: A phenoxy propanol derivative is provided to effectively suppress T-type calcium channel or TREK(TWIK-related K+)-1 channel and to treat various diseases. CONSTITUTION: A pharmaceutical composition for preventing or treating diseases related to T-type calcium channel or TREK-1 channel conta...

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Hauptverfasser: WOO, DONG HO, YANG, JEONG EUN, HWANG, EUN MI, OH, SOO JIN, CHUN, HEE JUNG, JI, WAN KEUN, LEE, SOON HYOUK, ROH, EUN JOO, KIM, DONG GYU, NA, YUN SOO, PARK, JUNG EUN, SHIN, KYE JUNG, LEE CHANGJOON JUSTIN
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:PURPOSE: A phenoxy propanol derivative is provided to effectively suppress T-type calcium channel or TREK(TWIK-related K+)-1 channel and to treat various diseases. CONSTITUTION: A pharmaceutical composition for preventing or treating diseases related to T-type calcium channel or TREK-1 channel contains a phenoxy propanol derivative with a structure of chemical formula I or a racemic body, a pharmaceutically acceptable salt, solvent, or hydrate thereof as an active ingredient. A method for suppressing the T-type calcium channel or TREK-1 channel comprises: a step of preparing a biological sample from organism; and a step of applying the phenoxy propanol derivative, or a racemic body, a pharmaceutically acceptable salt, solvate, or hydrate thereof.