SURFACE-ENHANCED RAMAN SCATTERING BASED MICROFLUIDIC CHIP FOR IMMUNOASSAY AND ON-CHIP IMMUNOASSAY USING THE SAME

PURPOSE: An SERS-based microfluidic chip for immunoassay and an on-chip immunoassay using the same are provided to enable automatic concentration gradient and replace a microtube set or micropipette. CONSTITUTION: An SERS-based microfluidic chip for immunoassay contains: antigen and buffer injection...

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Bibliographische Detailangaben
Hauptverfasser:	CHON, HYANG AH, LIM, CHAE SUNG, CHOO, JAE BUM
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	PURPOSE: An SERS-based microfluidic chip for immunoassay and an on-chip immunoassay using the same are provided to enable automatic concentration gradient and replace a microtube set or micropipette. CONSTITUTION: An SERS-based microfluidic chip for immunoassay contains: antigen and buffer injection unit formed independently; a gradient microfluid channel which is serially diluted and is connected to the antigen and buffer injection units; an antigen complex forming microfluid channel which is connected to the bottom of the gradient microfluid channel; a sandwich immunocomplex forming microfluid channel which is connected to the bottom of the antigen complex forming microfluid channel; and a trapping microfluid channel which is connected to the sandwich immunocomplex forming microfluid channel.