ITACONIC ACID HIGH PRODUCTIVE MUTANT STRAIN, METHOD FOR MANUFACTURING THE SAME, AND METHOD FOR PRODUCING ITACONIC ACID USING THE SAME

PURPOSE: A mutant strain which produces itaconic acid of high concentration is provided to prevent intracellular accumulation of itaconic acid and to obtain the itaconic acid of high yield. CONSTITUTION: A method for producing itaconic acid-producing strain of high productivity comprises: a step of...

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Hauptverfasser: KIM, SANG YONG, PARK, CHEOL HWAN, JO, JIN GU, SIN, WOO SIK, JEON, GYE TAEK, LEE, DO HOON
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:PURPOSE: A mutant strain which produces itaconic acid of high concentration is provided to prevent intracellular accumulation of itaconic acid and to obtain the itaconic acid of high yield. CONSTITUTION: A method for producing itaconic acid-producing strain of high productivity comprises: a step of inducing mutation of a strain; a step of selecting strains with reduced catabolite repression; a step of inducing mutation of the strain; and a step of selecting strains with enhanced membrane permeability. The strain is Aspergillus terreus 2DRNR(KACC 93094P). A method for producing itaconic acid comprises: a step of culturing the mutant strain; and a step of collecting the itaconic acid from the culture liquid.