PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING SYNOVIAL SARCOMA COMPRISING TLE1 INHIBITOR

PURPOSE: A pharmaceutical composition for preventing and treating synovial sarcoma is provided to ensure effective treatment. CONSTITUTION: A pharmaceutical composition for preventing and treating synovial sarcoma contains TLE1(transducin-like enhancer of split 1) gene inhibitor as an active ingredi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	SEO, SUNG WOOK, PARK, YOUN SOO, LEE, HEA WON
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	PURPOSE: A pharmaceutical composition for preventing and treating synovial sarcoma is provided to ensure effective treatment. CONSTITUTION: A pharmaceutical composition for preventing and treating synovial sarcoma contains TLE1(transducin-like enhancer of split 1) gene inhibitor as an active ingredient. The inhibitor is antisense oligonucleotide of TLE1 Mrna or siRNA of TLE1 gene. The siRNA has a base sequence selected from sequence numbers 1-5. The NCBI number of the TLE1 gene is NC_000009.11. A pharmaceutical composition for preventing and treating synovial sarcoma contains an inhibitor of proteins expressed from the TLE1 gene. The inhibitor of the protein is an antibody.