MOLECULAR PROBE FOR IMAGING OF PANCREATIC ISLET AND PRECURSOR THEREOF, AND USE OF THE MOLECULAR PROBE OR THE PRECURSOR

MOLECULAR PROBE FOR IMAGING OF PANCREATIC ISLET AND PRECURSOR THEREOF, AND USE OF THE MOLECULAR PROBE OR THE PRECURSOR

A precursor of molecular probe for imaging of pancreatic islets is provided. A polypeptide represented by any one of the following formulae (1) to (4), or a polypeptide having a homology with the foregoing polypeptide. *-DLSK* QMEEEAVRLFIEWLK* NGGPSSGAPPPSK-NH 2 (1) *-LSK* QMEEEAVRLFIEWLK* NGGPSSGAP...

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Bibliographische Detailangaben
Hauptverfasser: TOYODA KENTARO, NAGAKAWA KENJI, HIRAO KONOMU, INAGAKI NOBUYA, KIMURA HOROYUKI, SAJI HIDEO, OGAWA YU, MATSUDA HIROKAZU
Format: Patent
Sprache:eng ; kor
Schlagworte:
CHEMISTRY
CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS
GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC
GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE
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Zusammenfassung:A precursor of molecular probe for imaging of pancreatic islets is provided. A polypeptide represented by any one of the following formulae (1) to (4), or a polypeptide having a homology with the foregoing polypeptide. *-DLSK* QMEEEAVRLFIEWLK* NGGPSSGAPPPSK-NH 2 (1) *-LSK* QMEEEAVRLFIEWLK* NGGPSSGAPPPSK-NH 2 (2) *-SK* QMEEEAVRLFIEWLK* NGGPSSGAPPPSK-NH 2 (3) *-K* QMEEEAVRLFIEWLK* NGGPSSGAPPPSK-NH 2 (4), in the foregoing formulae (1) to (4) *- indicates that an ±-amino group at an N-terminus is protected by a protecting group or modified with a modifying group having no electric charge; K* indicates that an amino group of a side chain of a lysine is protected by a protecting group; and -NH 2 indicates that a carboxyl group at a C-terminus is amidated.