METHOD FOR DIAGNOSIS/PROGNOSIS OF CANCERS USING AN EPIGENETIC MARKER CONSISTING OF A SPECIFIC SINGLE CPG SITE IN TTP PROMOTER AND TREATMENT OF CANCERS BY REGULATING ITS EPIGENETIC STATUS

PURPOSE: A diagnosis for cancer using an epigenetic marker of specific single CpG site in TTP(Tristetraprolin) promoter and to treat and diagnose liver cancer. CONSTITUTION: A kit for diagnosing liver cancer contains a probe or primer pair which is able to detect methylation of cytosine residue of 3...

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Hauptverfasser: PARK, KYUNG CHAN, YEOM, YOUNG IL, SOHN, BO HWA, JANG, YE JIN, PARK, IN YOUNG, YANG, SUK JIN, YOO, HYANG SOOK, LEE, JUNG JU, CHOI, JONG YOUNG
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:PURPOSE: A diagnosis for cancer using an epigenetic marker of specific single CpG site in TTP(Tristetraprolin) promoter and to treat and diagnose liver cancer. CONSTITUTION: A kit for diagnosing liver cancer contains a probe or primer pair which is able to detect methylation of cytosine residue of 32th nucleic acid. The kit additionally contains reagent which modifies unmethylated cytosine residue. A pharmaceutical composition for preventing or treating liver cancer contains a material which suppresses methylation of cytosine residue as an active ingredient.