PYRAZOLO-PYRAZINES DERIVATIVES USED AS G PROTEIN INHIBITORS

The invention relates to pyrazolo-pyrazines derivatives of the general formula (I) in which the radicals Z, R, R, Rand Rrepresent various variable groups, X is a sulphur atom or a selenium atom, and n is an integer equal to 1 or 2. These compounds are inhibitors of G proteins. They are of particular...

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Bibliographische Detailangaben
Hauptverfasser:	BREHU LAETITIA, LAVERGNE OLIVIER, PREVOST GREGOIRE
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to pyrazolo-pyrazines derivatives of the general formula (I) in which the radicals Z, R, R, Rand Rrepresent various variable groups, X is a sulphur atom or a selenium atom, and n is an integer equal to 1 or 2. These compounds are inhibitors of G proteins. They are of particular interest for treating diseases in which the heterotrimeric G protein is involved. The invention also relates to pharmaceutical compositions containing said products, and to the use thereof for preparing a drug.