PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF HEPATITIS C VIRUS-MEDIATED LIVER DISEASE

An agent for preventing and treating hepatitis C virus-mediated liver disease is provided to suppress the enzyme activity of NS5B using monoclonal antibody which binds to N-terminal of NS5B protein. A pharmaceutical composition for preventing and treating hepatitis C virus-mediated liver disease com...

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Bibliographische Detailangaben
Hauptverfasser:	CHOI, SOO HO, HWANG, SOON BONG
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	An agent for preventing and treating hepatitis C virus-mediated liver disease is provided to suppress the enzyme activity of NS5B using monoclonal antibody which binds to N-terminal of NS5B protein. A pharmaceutical composition for preventing and treating hepatitis C virus-mediated liver disease comprises an anti-NS5B monoclonal antibody which binds to N-terminal of NS5B. The N-terminal is an amino acid region of 67-88. The hepatitis C virus-mediated liver disease is selected among acute hepatitis C virus, chronic hepatitis C, cirrhosis and liver cancer. The pharmaceutical composition is formulated with proper carrier based on the administration pathway.