COMPOUND AND ITS DERIVATIVES WHICH HAVE CARDIOMYOCYTE DIFFERENTIATING EFFECT FROM STEM CELLS

COMPOUND AND ITS DERIVATIVES WHICH HAVE CARDIOMYOCYTE DIFFERENTIATING EFFECT FROM STEM CELLS

A composition which promotes the differentiation from a stem cell to cardiac myocyte is provided to induce the differentiation or improve cardiac function. A compound which promotes the differentiation from a stem cell to cardiac myocyte is denoted by the chemical formula 1. The derivative of the co...

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Bibliographische Detailangaben
Hauptverfasser: KIM, HWAN MOOK, KANG, YONG KOOK, LEE, CHANG HEE, KIM, HYOUNG CHIN, OH, GOO TAEG, LEE, CHUL HO, KIM, EUN KYOUNG, NAM, KI HOAN, KIM, JANG HWAN, MOON, OG SUNG, SON, MI YOUNG, WON, YOUNG SUK
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:A composition which promotes the differentiation from a stem cell to cardiac myocyte is provided to induce the differentiation or improve cardiac function. A compound which promotes the differentiation from a stem cell to cardiac myocyte is denoted by the chemical formula 1. The derivative of the compound is denoted by the chemical formula 2. A method for inducing from the stem cell to cardiac myocyte comprises a step of culturing the stem cell in the presence of the compound of the derivative. In the chemical formula, R1 is selected from hydrogen, alkyl, alkoxy, hydroxy, halike, nitro, cyano, alkoxycarbonyl, amino group and substituted or non-substituted aryl group or heteroaryl group.