NOVEL 3-CHLORO-5-SUBSTITUTED-QUINOXALINE-2-AMINE DERIVATIVES AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD FOR PREPARATION, THERAPEUTIC AGENT FOR ANTIINFLAMMATORY DISEASE INDUCED BY SPC ACTIVITY CONTAINING 3-CHLORO-5-SUBSTITUTED-QUINOXALINE-2-AMINE DERIVATIVES AS AN EFFECTIVE INGREDIENT

Provided is a 3-chloro-5-substituted-quinoxaline-2-amine derivative and a therapeutic agent using the 3-chloro-5-substituted-quinoxaline-2-amine derivative so as to treat diseases associated with inflammation. A 3-chloro-5-substituted-quinoxaline-2-amine derivative is represented by the formula 1. I...

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Hauptverfasser: JEON, MOON KOOK, YUN, JUN WON, KIM, HYUK, KIM, JUNG JU, KIM, DO HOON, MOH, JOO HYUN, CHO, HEE YEONG, CHOI, GIL DON, KO, JAE YOUNG, KONG, JAE YANG, HWANG, SOON HEE, PARK, WOO KYU, LEE, TAE HO, GONG, YOUNG DAE, HAN, EUN SIL, NOH, MIN SOO, LEE, CHANG HOON
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Sprache:eng
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Zusammenfassung:Provided is a 3-chloro-5-substituted-quinoxaline-2-amine derivative and a therapeutic agent using the 3-chloro-5-substituted-quinoxaline-2-amine derivative so as to treat diseases associated with inflammation. A 3-chloro-5-substituted-quinoxaline-2-amine derivative is represented by the formula 1. In the formula 1, R∧1 indicates hydrogen, linear or branched C1-C10 alkyl group, C1-C10 alkoxy group or halogen; R∧2 shows linear or branched C1-C10 alkyl group, C1-C10 alkoxy group, hydroxyl group, halogen group, amine group or substituted amine group, amide group, carbamate group or urea group. In the formula 1, the substituted group indicates a substituted phenyl group wherein one or four groups selected from the group consisting of a linear or branched C1-C10 alkyl group, halogen, nitro group, C1-C10 alkyl group, C1-C10 alkoxy group and C1-C10 haloalkyl group are substituted.