COATED ANTIOXIDANT PARTICLE, COMPOSITION COMPRISING THE PARTICLE AND METHOD FOR PREPARING THE PARTICLE

COATED ANTIOXIDANT PARTICLE, COMPOSITION COMPRISING THE PARTICLE AND METHOD FOR PREPARING THE PARTICLE

A coated antioxidant particle is provided to enhance the stability of antioxidant, especially in the aqueous composition, and suppress the smell of alpha-lipoic acid by coating the antioxidant such as ascorbic acid with disulfide polymer of alpha-lipoic acid and optionally water-insoluble polymer. T...

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Hauptverfasser: KIM, CHUL HWAN, SHIN, CHAN JAE, KWON, JUNG AE, SEO, SO YEON
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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SHIN, CHAN JAE
KWON, JUNG AE
SEO, SO YEON
description A coated antioxidant particle is provided to enhance the stability of antioxidant, especially in the aqueous composition, and suppress the smell of alpha-lipoic acid by coating the antioxidant such as ascorbic acid with disulfide polymer of alpha-lipoic acid and optionally water-insoluble polymer. The coated antioxidant particle is comprised of an antioxidant compound core and a first coating layer containing alpha-lipoic acid based polymer, formed on the surface of the antioxidant compound core, and comprises 80-95 wt.% of antioxidant and 5-20 wt.% of polymer of alpha-lipoic acid, wherein the antioxidant compound is ascorbic acid, ascorbyl phosphate, glucosyl ascorbate, ascorbyl palmitate, catechin or epigallocatechin gallate(EGCG); the alpha-lipoic acid based polymer is alpha-lipoic acid, alpha-lipoic acid succinimide or alpha-lipoic acid glycine ester.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COATED ANTIOXIDANT PARTICLE, COMPOSITION COMPRISING THE PARTICLE AND METHOD FOR PREPARING THE PARTICLE
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