REMEDIES FOR BRAIN ISCHEMIC DISEASES

Remedies and/or preventives for brain ischemic diseases comprising two active ingredients, namely, an astrocytic function-improving agent, preferably a compound represented by the following general formula (I), and a thrombolytic agent, preferably a tissue plasminogen activator: (I) wherein R6 repre...

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Hauptverfasser:	TATEISHI NARITO, KATSUBE NOBUO, HONJO KANEYOSHI
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Remedies and/or preventives for brain ischemic diseases comprising two active ingredients, namely, an astrocytic function-improving agent, preferably a compound represented by the following general formula (I), and a thrombolytic agent, preferably a tissue plasminogen activator: (I) wherein R6 represents hydroxy, etc.; and (1) n is 1, R11 represents hydrogen, and R5 represents (alkyl having a fluorine atom as a substituent of a carbon atom)-CH2-; or (2) n is 0 or 1, R11 represents hydrogen, etc., and R5 represents alkyl, etc. These drugs show synergistic therapeutic effects compared with the case where an astrocytic function improving agent and a thrombolytic agent are separately administered.