ASYMMETRIC REDUCTION OF 1,1,1-TRIFLUOROACETONE

The invention relates to a scalable biocatalytic process for the preparation of S-1,1,1-trifluoro-2-propanol with a enantiomeric excess of > 99 % by asymmetric microbial reduction of 1,1,1-trifluoroacetone with Baker's yeast.

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Bibliographische Detailangaben
Hauptverfasser: HANLON STEVEN PAUL, DOSWALD STEPHAN, KUPFER ERNST
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to a scalable biocatalytic process for the preparation of S-1,1,1-trifluoro-2-propanol with a enantiomeric excess of > 99 % by asymmetric microbial reduction of 1,1,1-trifluoroacetone with Baker's yeast.