ANTI-WRINKLE COSMETIC COMPOSITION CONTAINING alpha;-KETOGLUTARATE

A cosmetic composition is provided to promote collagen biosynthesis by comprising alpha-ketoglutarate increasing the prolidase activity involving with the supply of proline, a main constituent amino acid of the collagen, together with alpha-lipoic acid increasing the expression of prolyl-4-hydroxyla...

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Bibliographische Detailangaben
Hauptverfasser: LEE, SO HEE, JANG, IH SEOP, SON, EUI DONG, KIM, HYAE KYOUNG, PARK, CHANG MAN, HWANG, JAE SUNG
Format: Patent
Sprache:eng
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Zusammenfassung:A cosmetic composition is provided to promote collagen biosynthesis by comprising alpha-ketoglutarate increasing the prolidase activity involving with the supply of proline, a main constituent amino acid of the collagen, together with alpha-lipoic acid increasing the expression of prolyl-4-hydroxylase to make a generated pro-collagen form a right triple helix. A cosmetic composition for improving skin wrinkle comprises 0.001-10 wt.% of alpha-ketoglutarate as an effective ingredient. The composition further comprises 0.001-10 wt.% of alpha-lipoic acid.