PYRAZOLO[1,5-A]PYRIDINE DERIVATIVE OR MEDICALLY ACCEPTABLE SALT THEREOF

PYRAZOLO[1,5-A]PYRIDINE DERIVATIVE OR MEDICALLY ACCEPTABLE SALT THEREOF

A pyrazolo[1,5-a]pyridine derivative represented by the formula (I) and a medically acceptable salt thereof have an excellent MAPKAP-K2 inhibitory activity. Therefore, a pharmaceutical comprising the compound as an active ingredient is expected to be useful for the treatment or prevention of a MAPKA...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MATSUEDA YOHEI, MATSUMOTO YOSHIYUKI, MAKINO HIROAKI, KATAOKA KENICHIRO, HAMADA MOTOKO, UNOKI GEN, TAKAKUWA MIKA, YAMAKOSHI YUKO, KOSUGI TOMOMI
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:A pyrazolo[1,5-a]pyridine derivative represented by the formula (I) and a medically acceptable salt thereof have an excellent MAPKAP-K2 inhibitory activity. Therefore, a pharmaceutical comprising the compound as an active ingredient is expected to be useful for the treatment or prevention of a MAPKAP-K2-mediated disorder such as an inflammatory disorder, an autoimmune disease, destructive osteopathy, cancer and/or tumor growth.