METHOD FOR PRODUCING PURINE NUCLEOSIDES AND NUCLEOTIDES BY FERMENTATION USING BACTERIUM BELONGING TO THE GENUS BACILLUS OR ESCHERICHIA

Methods for producing purine base analogues, purine nucleosides, and purine nucleotides, such as inosine and 5'-inosinic acid are provided which include using a bacterium belonging to the genus Bacillus or to the genus Escherichia wherein the purine productivity of said bacterium is enhanced by...

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Hauptverfasser:	NOVIKOVA ANNA EVGENIEVNA, GRONSKY SERGEY VIKTOROVICH, LIVSHITS VITALY ARKADIEVICH, KOZLOV YURI IVANOVICH, ZAKATAEVA NATALIA PAVLOVNA, KUTUKOVA EKATERINA ALEKSANDROVNA
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Zusammenfassung:	Methods for producing purine base analogues, purine nucleosides, and purine nucleotides, such as inosine and 5'-inosinic acid are provided which include using a bacterium belonging to the genus Bacillus or to the genus Escherichia wherein the purine productivity of said bacterium is enhanced by increasing an activity of the YdhL protein. Also disclosed is the amino acid sequence of the YdhL protein from Bacillus amyloliquefaciens and the gene encoding it. ® KIPO & WIPO 2007