COMPOUND HAVING AFFINITY WITH CALCIFIED TISSUE

A compound excelling in accumulation on calcified tissues, ensuring rapid excretion in the urine and rapid blood clearance, and being useful as a diagnostic agent or therapeutic agent. In particular, a compound having affinity with calcified tissues, represented by the formula (AC) a-MC-(LI)b wherei...

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Bibliographische Detailangaben
Hauptverfasser:	ITO OSAMU, KANAZASHI NOBUHIKO, KURAMI MIKI, MORISHITA AKI
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	A compound excelling in accumulation on calcified tissues, ensuring rapid excretion in the urine and rapid blood clearance, and being useful as a diagnostic agent or therapeutic agent. In particular, a compound having affinity with calcified tissues, represented by the formula (AC) a-MC-(LI)b wherein MC is a mother nucleus being a residue of compound having two or more functional groups selected from the group consisting of amino, amido, hydroxyl, thiol, thioether, sulfonyl, phosphonyl, aldehyde, carboxyl, carbonyl, halogen and cyano; AC is a group having affinity with calcified tissues; LI is a ligand capable of bonding with a metal atom; a is an integer of 1 or greater; and b is 0 or an integer of 1 or greater.