PHARMACEUTICAL COMPOSITION COMPRISING A LTB4 ANTAGONIST AND A COX-2 INHIBITOR OR A COMBINED COX 1/2 INHIBITOR

The invention relates to a pharmaceutical formulation comprising a LTB4 antagonist having a hydroxy and a benzamidine group or a tautomer, a pharmaceutically acceptable salt or solvate thereof, in particular a compound of formula (I), wherein R and A are as defined in the claims, or a tautomer, a ph...

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Hauptverfasser: JENNEWEIN HANS MICHAEL, BIRKE FRANZ
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to a pharmaceutical formulation comprising a LTB4 antagonist having a hydroxy and a benzamidine group or a tautomer, a pharmaceutically acceptable salt or solvate thereof, in particular a compound of formula (I), wherein R and A are as defined in the claims, or a tautomer, a pharmaceutically acceptable salt or solvate thereof (1) and at least one cyclooxygenase-2 inhibitor, a combined cox1/2 inhibitor or a pharmaceutically acceptable salt or solvate thereof (2), and a pharmaceutically acceptable carrier or excipient, and optionally one or more other therapeutic ingredients.