INHERITED HEAD TOSSING AND CIRCLING MUTANT MOUSE ADMINISTERED WITH N-ETHYL-N-NITROSOUREA

PURPOSE: Provided is a head tossing and circling mutant mouse that can be utilized in the research and the development of therapeutic agents for diseases associated with an organ of hearing and balancing, central nerves and a nerves system. CONSTITUTION: The head tossing and circling mutant mouse is produced by the process comprising the steps of: administering N-ethyl-N-nitrosourea into a male mouse; cross-breeding the above mouse with a normal mouse to obtain a 2nd generation mouse; back cross-breeding the obtained 2nd generation mouse with the above 1st generation mouse to obtain a 3rd generation mouse; and screening the mouse which exhibits head tossing and circling action from the obtained 3rd generation mouse. Particularly, the mouse is Musmusculus of BALB/c and N-ethyl-N-nitrosurea is administered in a concentration of 150 to 250 mg/kg.