7 Composition for preventing the formation of new scar comprising BMP-7

PURPOSE: Provided is a composition for preventing the formation of a scar comprising BMP-7. Particularly, the composition is an inhibitor of the transformation of myofibroblasts. CONSTITUTION: A composition for preventing the formation of a scar is characterized by containing an effective amount of...

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Bibliographische Detailangaben
Hauptverfasser: HUH, JEONG HYEON, CHO, YANG JE, JANG, MYEONG JIN, LEE, IN SIK, YOO, WON IL, AHN, BO YEONG
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:PURPOSE: Provided is a composition for preventing the formation of a scar comprising BMP-7. Particularly, the composition is an inhibitor of the transformation of myofibroblasts. CONSTITUTION: A composition for preventing the formation of a scar is characterized by containing an effective amount of BMP-7 polypeptide set forth in SEQ ID NO:1 and extracted from the amnion. Particularly, the BMP-7 polypeptide is contained in the composition in the amount of 50ng/ml to 50ug/ml or 0.1ng/kg to 1ug/kg. 본 발명은 BMP(본 모포제닉프로테인)-7 폴리펩타이드를 포함하는 흉터조직 형성을 억제제에 대한 발명으로 더욱 상세하게는 BMP-7 폴리펩타이드를 포함하는 마이오피브로브라스트 형성 억제제에 대한 발명이다.