METHOD AND REAGENTS FOR CELL TRANSPLANTATION

PURPOSE: A method and reagents for cell transplantation are provided, thereby increasing the engraftment rate and survival rate of the cell. CONSTITUTION: A method for producing cells for transplantation into the myocardial tissue of a mammal comprises the steps of: (a) providing a population of bon...

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Bibliographische Detailangaben
Hauptverfasser:	CROISSANT, JEFFREY, D, LIU, GUIZHEN, LEE, IKE, W, HAMPE, JAMES
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	BEER BIOCHEMISTRY CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ENZYMOLOGY HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	PURPOSE: A method and reagents for cell transplantation are provided, thereby increasing the engraftment rate and survival rate of the cell. CONSTITUTION: A method for producing cells for transplantation into the myocardial tissue of a mammal comprises the steps of: (a) providing a population of bone marrow stem cells; (b) culturing the cells under conditions for the cells to become cardiomyogenic cells; (c) monitoring the state of differentiation of the cells of step (b); and (d) collecting the cells of step (b) when at least about 10% and as many as 100% of the cells become cardiomyogenic cells, wherein the bone marrow stem cells can be human bone marrow stem cells; and the differentiated stem cells are further transplanted into a mammal.