METHOD FOR PREPARING (RR,SS)-4,8-DIAZA-3,6,6,9-TETRAMETHYLUNDECANE-2,10-DION BISOXIME DERIVATIVE

PURPOSE: Methods for preparing pure d,l-hexamethyl propyleneamine oxime named as(RR,SS)-4,8-diaza-3,6,6,9-tetramethylundecane-2,10-dion bisoxime derivative without contamination of other meso isomer are provided. CONSTITUTION: A mixed compound of the following formula 15a and 15b is prepared by reacting the mixed compound of the following formula 14a and 14b with appropriate solvent and appropriate deprotecting agent, where R is selected from the group consisting of linear or branched low alkyl having 1-6 carbon atoms, the ring represented by -(CH2)n- or the ring represented by -(CH2)a-X-(CH2)b-, where X is selected from the group consisting of N, O and S, and n, a and are independently 1-10; R1 is linear or branched low alkyl having 1-6 carbon atoms; R2 is selected from the group consisting of linear or branched low alkyl, low alkene or low alkyne having 1-10 carbon atoms; R3 is selected from the group consisting of H, linear or branched low alkyl having 1-6 carbon atoms and benzyl; and P is an acyl halide derivative which is able to form amide group by binding with secondary amine.