DIRECTLY COMPRESSIBLE LACTITOL AND METHOD THEREOF
PURPOSE: A lactitol offers an aqueous solubility which is similar to sucrose which contributes to its ability to provide a smooth, non-chalky mouth feel and suitable release of active ingredients. CONSTITUTION: A directly compressible non-carcinogenic free-flowing lactitol granulate comprises milled...
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Zusammenfassung: | PURPOSE: A lactitol offers an aqueous solubility which is similar to sucrose which contributes to its ability to provide a smooth, non-chalky mouth feel and suitable release of active ingredients. CONSTITUTION: A directly compressible non-carcinogenic free-flowing lactitol granulate comprises milled lactitol and a physiologically acceptable, binder taken from the group consisting of sugar alcohols, polymerized reducing sugars, alkali carboxy methyl cellulose, hydrogenated starch hydrolysate, hydroxypropyl cellulose, physiologically acceptable cellulose derivatives, polyvinylpyrrolidone, gum arabic, and other physiologically acceptable gums. The granulate is directly compressible, and manifests the taste profile, metabolic, and non-carcinogenic properties of lactitol. The milled lactitol is present in the granulate in the range of about 70% to about 98% by dry weight and the physiologically acceptable, non-carcinogenic binder is present in the granulate in the range of about 2% to about 30% by dry weight. The granulate consists of 70-98% milled lactitol and 2-30% of a lactitol binder. |
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